BOC-Asp(OMe)-FMK [Boc-D(OMe)-FMK] CAS 187389-53-3

	货号	5310	存储条件	在零下15度以下保存, 避免光照
	规格	1 mg	价格	1272
	Ex (nm)		Em (nm)
	分子量	263.27	溶剂	DMF
	产品详细介绍

简要概述

产品基本信息

货号：5310

产品名称：BOC-Asp(OMe)-FMK [Boc-D(OMe)-FMK]

CAS：187389-53-3

规格：1mg

储存条件：-15℃避光防潮

保质期：12个月

产品物理化学光谱特性

分子量：263.27

溶剂：DMF

激发波长（nm）：N/A

发射波长（nm）：N/A

产品介绍

FMK肽是有效的，可透过细胞的，不可逆的capase抑制剂。它可用于检测和监测体外和体内应用中的细胞凋亡。BOC-ASP（OMe）-FMK是开发和制备基于FMK的capase抑制剂和探针的关键中间体。基于Asp（OMe）-FMK的半胱天冬酶抑制剂是细胞可渗透的并且不可逆地结合活化的半胱天冬酶以阻断细胞凋亡。作为分子链锯的胱天蛋白酶是细胞凋亡反应的核心组成部分。半胱天冬酶是半胱氨酸蛋白酶，其天冬氨酸残基在其底物中裂解。14种已知的哺乳动物半胱天冬酶中至少有7种在细胞凋亡中起重要作用。金畔生物是AAT Bioquest的中国代理商，为您提供最优质的BOC-Asp(OMe)-FMK [Boc-D(OMe)-FMK]。

参考文献

A glycine-leucine-rich peptide structurally related to the plasticins from skin secretions of the frog Leptodactylus laticeps (Leptodactylidae)
Authors: Conlon JM, Abdel-Wahab YH, Flatt PR, Leprince J, Vaudry H, Jouenne T, Condamine E.
Journal: Peptides (2009): 888

Design of nontoxic analogues of cathelicidin-derived bovine antimicrobial peptide BMAP-27: the role of leucine as well as phenylalanine zipper sequences in determining its toxicity
Authors: Ahmad A, Azmi S, Srivastava RM, Srivastava S, Pandey BK, Saxena R, Bajpai VK, Ghosh JK.
Journal: Biochemistry (2009): 10905

Leucine-rich amelogenin peptide induces osteogenesis by activation of the Wnt pathway
Authors: Warotayanont R, Frenkel B, Snead ML, Zhou Y.
Journal: Biochem Biophys Res Commun (2009): 558

Leucine-rich amelogenin peptide induces osteogenesis in mouse embryonic stem cells
Authors: Warotayanont R, Zhu D, Snead ML, Zhou Y.
Journal: Biochem Biophys Res Commun (2008): 1

Leucine-rich glioma inactivated 3 is involved in amyloid beta peptide uptake by astrocytes and endocytosis itself
Authors: Okabayashi S, Kimura N.
Journal: Neuroreport (2008): 1175

Leucine 7-proline 7 polymorphism in the signal peptide of neuropeptide Y is not a risk factor for exudative age-related macular degeneration
Authors: Kaarniranta K, Holopainen JM, Karvonen MK, Koulu M, Kallio J, Pesonen U, Terasvirta M, Uusitalo H, Immonen I.
Journal: Acta Ophthalmol Scand (2007): 188

Peptide-phospholipid cross-linking reactions: identification of leucine enkephalin-alka(e)nal-glycerophosphatidylcholine adducts by tandem mass spectrometry
Authors: Reis A, Domingues P, Ferrer-Correia AJ, Domingues MR.
Journal: J Am Soc Mass Spectrom (2006): 657

131I-Labeled arginine-arginine-leucine (RRL)-containing cyclic peptide (YCGGRRLGGC) for imaging prostate carcinoma
Authors: Shan L
Journal: (2004)

Leucine-rich amelogenin peptide: a candidate signaling molecule during cementogenesis
Authors: Boabaid F, Gibson CW, Kuehl MA, Berry JE, Snead ML, Nociti FH, Jr., Katchburian E, Somerman MJ.
Journal: J Periodontol (2004): 1126

Cloning the tomato curl3 gene highlights the putative dual role of the leucine-rich repeat receptor kinase tBRI1/SR160 in plant steroid hormone and peptide hormone signaling
Authors: Montoya T, Nomura T, Farrar K, Kaneta T, Yokota T, Bishop GJ.
Journal: Plant Cell (2002): 3163