胱天蛋白酶Caspase抑制剂Z-DEVD-FMK

	货号	13303	存储条件	在零下15度以下保存, 避免光照
	规格	1 mg	价格	1200
	Ex (nm)		Em (nm)
	分子量	668.67	溶剂	DMSO
	产品详细介绍

简要概述

产品基本信息

货号：13303

产品名称：胱天蛋白酶Caspase抑制剂Z-DEVD-FMK

规格：1mg

储存条件：-15℃避光防潮

保质期：12个月

产品物理化学光谱特性

分子量：668.67

溶剂：DMSO

产品介绍

Z-DEVD-FMK是一种不可逆的特异性Caspase-3抑制剂，对caspase-6，caspase-7，caspase-8和caspase-10也具有有效的抑制作用。金畔生物是AAT Bioquest的中国代理商，为您提供最优质的Z-DEVD-FMK。 

参考文献

Rescue of Escherichia coli cells from UV-induced death and filamentation by caspase-3 inhibitor.
Authors: Wadhawan, Surbhi and Gautam, Satyendra
Journal: International microbiology : the official journal of the Spanish Society for Microbiology (2019): 369-376

AGEs Induce Apoptosis in Rat Osteoblast Cells by Activating the Caspase-3 Signaling Pathway Under a High-Glucose Environment In Vitro.
Authors: Liu, Jiaqiang and Mao, Jing and Jiang, Yi and Xia, Lunguo and Mao, Lixia and Wu, Yong and Ma, Pan and Fang, Bing
Journal: Applied biochemistry and biotechnology (2016): 1015-27

Cleavage of the calpain inhibitor, calpastatin, during postmortem ageing of beef skeletal muscle.
Authors: Huang, Feng and Huang, Ming and Zhang, Hong and Guo, Bing and Zhang, Dequan and Zhou, Guanghong
Journal: Food chemistry (2014): 1-6

Increased activity of cell surface peptidases in HeLa cells undergoing UV-induced apoptosis is not mediated by caspase 3.
Authors: Piva, Terrence J and Davern, Catherine M and Hall, Paula M and Winterford, Clay M and Ellem, Kay A O
Journal: International journal of molecular sciences (2012): 2650-75

Lysosomal membrane permeabilization is an early event in Sigma-2 receptor ligand mediated cell death in pancreatic cancer.
Authors: Hornick, John R and Vangveravong, Suwanna and Spitzer, Dirk and Abate, Carmen and Berardi, Francesco and Goedegebuure, Peter and Mach, Robert H and Hawkins, William G
Journal: Journal of experimental & clinical cancer research : CR (2012): 41

Caspase 3 blocking avoids the expression of autoantigens triggered by apoptosis in neonatal Balb/c mice skin.
Authors: Ramírez-Sandoval, R and Vazquez-del-Mercado, M and Daneri-Navarro, A and Bollain-y-Goytia, J J and Avalos-Diaz, E and Herrera-Esparza, R
Journal: Reumatismo (2011): 29-37

Disassembly of the JIP1/JNK molecular scaffold by caspase-3-mediated cleavage of JIP1 during apoptosis.
Authors: Vaishnav, Mahesh and MacFarlane, Marion and Dickens, Martin
Journal: Experimental cell research (2011): 1028-39

Role of VPO1, a newly identified heme-containing peroxidase, in ox-LDL induced endothelial cell apoptosis.
Authors: Bai, Yong-Ping and Hu, Chang-Ping and Yuan, Qiong and Peng, Jun and Shi, Rui-Zheng and Yang, Tian-Lun and Cao, Ze-Hong and Li, Yuan-Jian and Cheng, Guangjie and Zhang, Guo-Gang
Journal: Free radical biology & medicine (2011): 1492-500

Evidence for caspase effects on release of cytochrome c and AIF in a model of ischemia in cortical neurons.
Authors: Singh, Maneesh H and Brooke, Sheila M and Zemlyak, Ilona and Sapolsky, Robert M
Journal: Neuroscience letters (2010): 179-83

Proteasome activity profiling: a simple, robust and versatile method revealing subunit-selective inhibitors and cytoplasmic, defense-induced proteasome activities.
Authors: Gu, Christian and Kolodziejek, Izabella and Misas-Villamil, Johana and Shindo, Takayuki and Colby, Tom and Verdoes, Martijn and Richau, Kerstin H and Schmidt, Jürgen and Overkleeft, Hermen S and van der Hoorn, Renier A L
Journal: The Plant journal : for cell and molecular biology (2010): 160-70